Disrupted mucus transport is a hallmark of many lung diseases.
We can measure how well human lung tissue transports mucus in a dish:
e.g., by tracking the motion of beads propelled by these cells in vitro

Physiological phenotypes are the foundation of our approach to drug discovery. Whether we’re finding targets or making molecules, we optimize outcomes in patient-derived tissues that mirror what happens in humans.

While complex, organotypic cultures can be highly predictive,
they’re also hard to automate.

So, we’ve developed active learning algorithms
to run the right experiments at the right scale for causal target discovery.

We map molecular state to tissue function with unprecedented efficiency
to discover drug targets that translate.